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Ovarian Cancer

New ovarian cancer study findings have been reported by J.M. Riedinger and co-researchers

Published in Cancer Weekly, July 15th, 2008

"CA 125 assays enable treatment-response monitoring in ovarian cancer. A multicentric study of CA 125 kinetics under paclitaxel/platinum-based chemotherapy was performed in 130 stage IIc-IV patients," investigators in Dijon, France report.

"CA 125 half-life and nadir concentration were compared to patient outcome. Some patients (n=38, 29.2%) presented a CA 125 bi-exponential decrease and its clinical implication was studied. Survival analyses for disease-free survival (DFS) and overall survival (OS) used univariate (Kaplan-Meier) and multivariate (Cox model). During a median follow-up time of 29 months (range 5-106 months), 111 patients (85%) relapsed and 94 (72%) died...

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