Cancer Weekly
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Cancer Vaccines Immunology
Data on cancer vaccines immunology published by researchers at Roswell Park Cancer Institute
July 15th, 2008
Data detailed in 'Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1' have been presented. According to recent research published in the journal Cancer Immunology, Immunotherapy, "NY-ESO-1 is frequently expressed in epithelial ovarian cancer (EOC) and elicits spontaneous humoral and cellular immune responses in a proportion of EOC patients. The identification of NY-ESO-1 peptide epitopes with dual HLA-class I and class II specificities might be useful in vaccination strategies for generating cognate CD4+ T cell help to augment CD8+ T cell responses." "Here, we describe...
Source: Cancer Weekly (2008-07-15)
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