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Bayer HealthCare Pharmaceuticals Inc.

Journal of Clinical Oncology Publishes Leukine Study Demonstrating Positive Survival Outcomes in Patients with High-Risk Melanoma

Published in Cancer Weekly, July 15th, 2008

Bayer HealthCare Pharmaceuticals confirmed that results of a Phase II trial were published in the July 1 edition of the Journal of Clinical Oncology. The study showed that Leukine(R) (sargramostim) demonstrated a median overall survival of 65 months and increased mature dendritic cells in high-risk melanoma patients. Dendritic cells are special antigen-presenting cells that help the immune system recognize cancer cells and are the most effective antigen-presenting cells known. Study authors concluded that this increase in dendritic cell counts may also correlate with delayed recurrence of disease.

"These data provide early signals that Leukine may offer clinical benefit...

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