Cancer Weekly
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Astrocytoma
Findings from F.M. Iwamoto and co-authors provide new insights into astrocytoma
July 15th, 2008
" To assess the frequency of chromosomes 1p and 19q deletions in gliomas and to correlate 1p deletion with prognosis in patients with grade 2 and grade 3 gliomas independently of histologic subtype. We retrospectively evaluated 208 patients with WHO grade 2 and 3 gliomas who had 1p/19q molecular studies performed between 2000 and 2004," scientists in the United States report. "DNA was extracted from tumor tissue and germline material and evaluated by PCR using microsatellite markers for each chromosome. There were 113 men and 95 women with a median age at diagnosis of 40. Thirty-eight patients had a low-grade astrocytoma (A2), 58 low-grade oligodendroglioma (O2), 31...
Source: Cancer Weekly (2008-07-15)
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