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Cancer Weekly

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Cancer Gene Therapy



Study results from St. Vincent's Hospital, Department of Orthopaedics in the area of cancer gene therapy published



July 22nd, 2008

Data detailed in 'C-jun: pharmaceutical target for DNAzyme therapy of multiple pathologies' have been presented. According to a study from Melbourne, Australia, "Recent studies have demonstrated the potential of DNAzymes for therapy of various diseases via mRNA target-specific cleavage. One such target, the basic region-leucine zipper protein c-Jun, has been targeted and efficacy seen in such pathologies as cancer, ocular neovascularisation, arterial thickening, acute inflammation, and rheumatoid arthritis."

"This review discusses these cases in turn, and presents some new data on the applicability of a c-jun DNAzyme against a panel of cancer cells. Importantly,...


Source: Cancer Weekly (2008-07-22)

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