Drug Delivery
Scientists at Rutgers University release new data on drug delivery
Published in Cancer Weekly, July 22nd, 2008
In this recently published study, investigators in the United States conducted a study "To enhance the efficacy of cancer treatment, we propose a complex approach: simultaneous delivery to the tumor of a chemotherapeutic agent and a suppressor of hypoxia-inclucible factor alpha (HIF1A). The novel complex liposomal drug delivery system was developed and evaluated in vitro and in vivo on nude mice bearing xenografts of multidrug-resistant human ovarian carcinoma."
"The proposed novel complex drug delivery system consists of liposomes as a nanocarrier, a traditional anticancer drug (doxorubicin) as a cell death inducer, and antisense oligonucleoticles targeted to HIF1A...
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Source: Cancer Weekly (2008-07-22)
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