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Cancer Vaccines
Scientists at Brigham and Women's Hospital discuss research in cancer vaccines
July 22nd, 2008
New investigation results, 'Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells,' are detailed in a study published in The Journal of Immunology. According to a study from the United States, "Vaccination of patients with dendritic cell (DC)/breast carcinoma fusions stimulated antitumor immune responses in a majority of patients with metastatic disease but only a subset demonstrate evidence of tumor regression. To define the factors that limit vaccine efficacy, we examined the biological characteristics...
Source: Cancer Weekly (2008-07-22)
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