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Cancer Vaccines Immunology
Data on cancer vaccines immunology reported by researchers at University of Florida, Department of Urology
July 22nd, 2008
Fresh data on cancer vaccines are presented in the report 'Oxidative stress regulates expression of VEGFR1 in myeloid cells: link to tumor-induced immune suppression in renal cell carcinoma.' "Metastatic renal cell carcinoma (RCC) associates with overproduction of vascular endothelial growth factor (VEGF) due to the mutation/inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene. Herein we demonstrate that implantation of human RCC tumor cells into athymic nude mice promotes the appearance of VEGF receptor 1 (VEGFR1)/CD11b double-positive myeloid cells in peripheral blood," researchers in the United States report. "Avastin-mediated VEGF neutralization was...
Source: Cancer Weekly (2008-07-22)
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