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Gene Therapy
Tsinghua University, National Laboratory of Medical Molecular Biology describes research in gene therapy
July 22nd, 2008
Fresh data on gene therapy are presented in the report 'AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice.' According to recent research from Beijing, People's Republic of China, "A major obstacle in the development of effective recombinant adeno-associated virus (rAAV) mediated gene therapy is infection specificity and gene targeting. In the present study, we investigated whether the human telomerase reverse transcriptase (hTERT) promoter could drive tumor-specific expression of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), an apoptosis apoptosis-inducing protein with potential toxic effects on...
Source: Cancer Weekly (2008-07-22)
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