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Cancer Weekly

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Retinoblastoma Gene Therapy



Researchers from University Hospital, Department of Pathology publish findings in retinoblastoma gene therapy



July 22nd, 2008

Scientists discuss in 'Retinoblastoma (Rb) tumor-suppressor pathway alterations in meningeal hemangiopericytomas: High E2F transcription factor 1 expression and loss of Rb expression: study by double immunofluorescence staining and laser-scanning confocal microscopy' new findings in retinoblastoma. According to recent research from Madrid, Spain, "The authors analyzed the retinoblastoma (Rb) tumor-suppressor pathway in meningeal hemangiopericytomas (MHPCs). METHODS.: Immunohistochemical detection of the Rb pathway proteins (Rb; E2F transcription factor 1 [E2F1]; cyclins D1, D3, and E; cyclin-dependent kinase 4 [CDK4]; and the CDK4 inhibitor p16/INKa) was followed by double...


Source: Cancer Weekly (2008-07-22)

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