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University of Pittsburgh Schools of the Health Sciences
Hepatitis C virus may need enzyme's help to cause liver disease
July 22nd, 2008
A key enzyme may explain how hepatitis C infection causes fatty liver – a buildup of excess fat in the liver, which can lead to life-threatening diseases such as cirrhosis and liver cancer, report University of Pittsburgh Graduate School of Public Health and School of Medicine researchers. The study, published in the July 9 online issue of Hepatology, shows that an enzyme known to play a major role in lipid production, fatty acid synthase (FAS), was highly elevated in human liver cells exposed to the hepatitis C virus. While preliminary, the research suggests that testing for elevated levels of FAS could help determine which patients with hepatitis C virus may go on to...
Source: Cancer Weekly (2008-07-22)
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