Cancer Weekly
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Adenoma
New adenoma research from S. Ferreira and co-researchers described
July 22nd, 2008
According to recent research from Lisbon, Portugal, "Original Bethesda Guidelines proposed microsatellite instability analysis in colorectal adenomas from patients younger than aged 40 years to identify new cases of Lynch syndrome. We intended to evaluate the characteristics of colorectal adenomas from patients younger than aged 40 years to determine their microsatellite instability status and to correlate it with germline mutations in MLH1 and MSH2 genes." "Seventy-two adenomas from 58 patients were analyzed. Family history of colorectal cancer, location, and histology of adenomas were evaluated. Microsatellite instability testing was performed with BAT26 only or with...
Source: Cancer Weekly (2008-07-22)
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