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Cancer Weekly

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Allograft Vasculopathy



Reports by L. Potena and co-researchers describe recent advances in allograft vasculopathy



July 22nd, 2008

According to a study from Bologna, Italy, "Folic acid therapy reduces homocysteine plasma levels, which seem to influence occurrence of cardiac allograft vasculopathy, but its effect on medium- or long-term prognosis after heart transplantation is unknown. We analyzed 7-year outcome of 51 recipients randomized to receive 15 mg/day of methyltertrahydrofolate for I year after heart transplantation or standard therapy alone (originally, for intravascular ultrasound study of short-term cardiac allograft vasculopathy progression); recipients were observed for a further 5 to 6 years."

"Overall, 13 deaths occurred (six oncologic, five cardiovascular, two infective). Estimated...


Source: Cancer Weekly (2008-07-22)

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