Cancer Weekly
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Angiogenesis
Research conducted at Mayo Clinic has updated our knowledge about angiogenesis
July 22nd, 2008
"Angiogenesis, one of the hallmarks of cancer, has recently become the target of therapeutic approaches in oncology. Among the complex system of pro- and antiangiogenic factors, the vascular endothelial growth factor system stands out as key mediator of tumor-initiated angiogenesis and as target of antiangiogenesis agents introduced in clinical practice," scientists in the United States report. "Although antivascular endothelial growth factor therapies, and in particular, bevacizumab as monoclonal antibody against vascular endothelial growth factor has clearly demonstrated antitumor efficacy, its mechanism of action is not fully understood. This review will discuss the...
Source: Cancer Weekly (2008-07-22)
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