Cancer Weekly
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Angiogenesis
Research conducted at S. Ponticelli and co-researchers has updated our knowledge about angiogenesis
July 22nd, 2008
"The activation of vascular endothelial growth factor receptor-1 (VEGFR-1, also known as Flt-1) is crucial in many physiological and pathological conditions, like angiogenesis, cancer, inflammation, hematopoiesis, bone marrow precursors/stem cells recruitment in tumor angiogenesis, and metastasis formation. Many recent reports indicate that molecules able to antagonize Flt-1 activity have gained a strong interest in the view of therapeutic approaches," scientists writing in the journal Planta Medica report. "In order to identify new compounds able to interfere in the Flt-1 recognition by VEGFs family members, we have developed a highly sensitive competitive...
Source: Cancer Weekly (2008-07-22)
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