Cancer Weekly
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Cancer Gene Therapy
New cancer gene therapy research has been reported by scientists at Third Military Medical University
July 22nd, 2008
According to a study from Chongqing, People's Republic of China, "Human lung carcinoma is a highly metastatic tumour that leads to a high death rate and in which lymphatic metastasis is an important early event. HYA (hyaluronan) is involved in the invasion of a variety of tumour cells." "Layilin, a specific and novel HYA receptor, was detected in the human lung cell line A549 in our preliminary research, and was hypothesized to play an essential role in cell motility and tumour lymphatic metastasis. In the present study we found that, as expected, suppression of layilin expression by RNA interference significantly inhibited A549-cell invasion and migration in vitro and...
Source: Cancer Weekly (2008-07-22)
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