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Clinical Trial Research

Studies from Hirosaki University, Medical Department provide new data on clinical trial research

Published in Cancer Weekly, July 29th, 2008

"To evaluate the effectiveness and side effects of prophylactic low-dose bacille Calmette-Guerin (BCG) Tokyo 172 strain. We conducted a historical cohort study to compare the clinical usefulness of standard-dose versus low-dose BCG Tokyo 172 strain," researchers in Hirosaki, Japan report.

"A total of 156 patients with superficial bladder cancer (Stage Ta-T1) were historically allocated to either 40 or 80 mg of BCG after transurethral resection. Of the 156 patients, 89 had received standard-dose (80 mg) BCG from 1988 to 2000 and 67 had received low-dose (40 mg) BCG from 1996 to 2005. BCG was instilled into the bladder once a week for 6 consecutive weeks. We excluded 6...

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