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Cancer Vaccines
Studies from P. Kiewe et al in the area of cancer vaccines described
July 29th, 2008
According to a study from Munich, Germany, " Most cancer vaccination trials have been performed in human leukocyte antigen (HLA)-A2 positive populations. Some studies have used HLA-A2 negative patients as control group." "However, HLA-type and HLA-expression can interact with tumor biology and possibly affect prognosis. HLA-A2 negative patients might constitute an inadequate control group. Materials and methods Patients with colorectal cancer were serologically analyzed for HLA-A2 expression. Patients were evaluated for tumor stage, grading, tumor location. Overall survival (OAS) of HLA-A2 positive and HLA-A2 negative patients was compared. One hundred forty-four...
Source: Cancer Weekly (2008-07-29)
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