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Cancer Weekly

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Hepatitis C Virus



Study data from R. Thimme et al provide new insights into hepatitis C virus



July 29th, 2008

According to a study from Freiburg, Germany, "Hepatitis C virus (HCV) causes chronic infection in approximately two-thirds of cases, leading to chronic hepatitis, liver cirrhosis, liver disease, liver failure, and hepatocellular carcinoma in a substantial proportion of the 170 million HCV-infected individuals worldwide. It is generally accepted that the cellular immune response plays the most important role in determining the outcome of HCV infection."

"First, vigorous, multispecific and sustained CD4(+) and CD8(+) T-cell responses are associated with viral clearance. Second, depletion studies in chimpanzees, the only other host of HCV besides humans, have shown that...


Source: Cancer Weekly (2008-07-29)

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