Cancer Weekly
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Cancer Gene Therapy
Findings in cancer gene therapy reported from Cell Genesys, Inc.
July 29th, 2008
Research findings, 'Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models,' are discussed in a new report. According to recent research published in the journal Clinical Cancer Research, "Evaluate the codelivery of hyaluronidase enzyme with oncolytic adenoviruses to determine whether it improves the spread of the virus throughout tumors, thereby leading to a greater overall antitumor efficacy in tumor models. The optimal dose of hyaluronidase that provided best transduction efficiency and spread of a green fluorescent protein (GFP)-expressing adenovirus within tumors was combined with oncolytic viruses in...
Source: Cancer Weekly (2008-07-29)
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