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Cancer Weekly

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Cancer Gene Therapy



New cancer gene therapy data have been reported by scientists at University of Pittsburgh, Department of Pathology



July 29th, 2008

Researchers detail in 'Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth,' new data in cancer gene therapy. According to a study from the United States, "The rhomboid family of genes carry out a wide range of important functions in a variety of organisms. Little is known, however, about the function of the human rhomboid family-1 gene (RHBDF1)."

"We show here that RHBDF1 function is essential to epithelial cancer cell growth. RHBDF1 mRNA level is significantly elevated in clinical specimens of invasive ductal carcinoma of the breast, and the protein is readily detectable in human breast...


Source: Cancer Weekly (2008-07-29)

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