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Cancer Weekly

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Cancer Gene Therapy



Research on cancer gene therapy reported by scientists at Duke University, Comprehensive Cancer Center



July 29th, 2008

Investigators publish new data in the report 'Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene.' According to recent research from the United States, "The glutathione S-transferase P1 (GSTP1) is involved in multiple cellular functions, including phase II metabolism, stress response, signaling, and apoptosis. The mechanisms underlying the significantly high GSTP1 expression in many human tumors are, however, currently not well understood."

"We report here that the GSTP1 gene is a heretofore unrecognized downstream transcriptional target of the tumor suppressor...


Source: Cancer Weekly (2008-07-29)

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