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Cancer Weekly

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Bone Marrow



Study data from C. Dufour et al provide new insights into bone marrow



July 29th, 2008

"Fanconi anaemia (FA) is a rare genetic disease characterized by chromosomal instability, somatic abnormalities, marrow failure and cancer proness. The main cause of morbidity and mortality is bone marrow failure, which typically arises in the first decade of life and progresses to full-blown transfusion dependence and severe neutropenia in a variable number of years," researchers in Genoa, Italy report.

"Myelodysplastic syndrome (MDS) and AML may arise on the background of marrow failure, although cases of patients diagnosed with MDS or overt leukaemia before the full appearance of marrow aplasia are reported. This article reviews the current options for treatment of...


Source: Cancer Weekly (2008-07-29)

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