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Cancer Vaccines Therapy
Findings from Y. Sun et al in cancer vaccines therapy reported
July 29th, 2008
Investigators publish new data in the report 'Human CD4+ T lymphocytes recognize a vascular endothelial growth factor receptor-2-derived epitope in association with HLA-DR.' According to recent research from Langen, Germany, "Given the multiple escape mechanisms of tumor cells, immunotherapy targeting tumor-dependent stroma may be an effective cancer treatment strategy. Animal models indicate that inducing immunity to tumor endothelia engenders potent antitumor effects without significant pathology." "Recently, the first human tumor endothelial antigen vascular endothelial growth factor receptor-2 (VEGFR-2) recognized by HLA class I-restricted CD8(+) T cells has been...
Source: Cancer Weekly (2008-07-29)
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