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Neuroblastoma Gene Therapy
Scientists at Children's Hospital, Division of Oncology discuss research in neuroblastoma gene therapy
July 29th, 2008
Researchers detail in 'A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene,' new data in neuroblastoma. According to recent research from the United States, "MicroRNAs are small noncoding RNAs that have critical roles in regulating a number of cellular functions through transcriptional silencing. They have been implicated as oncogenes and tumor suppressor genes (oncomirs) in several human neoplasms." "We used an integrated genomics and functional screening strategy to identify potential oncomirs in the pediatric neoplasm neuroblastoma. We first identified microRNAs that map within chromosomal regions that we and others have defined...
Source: Cancer Weekly (2008-07-29)
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