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Cancer Weekly

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Acute Lymphoblastic Leukemia



Studies conducted at University of Minnesota, Medical Department on acute lymphoblastic leukemia recently published



July 29th, 2008

According to recent research published in the journal Blood, "Survivors of childhood acute lymphoblastic leukemia (ALL) are at risk for late effects of cancer therapy. Five-year ALL survivors (< 21 years at diagnosis; n = 5760 eligible, 4151 participants), diagnosed from 1970 to 1986 were compared with the general population and a sibling cohort (n = 3899)."

"Cumulative mortality of 5760 5-year survivors was 13% at 25 years from diagnosis. Recurrent ALL (n = 483) and second neoplasms (SNs; n = 89) were the major causes of death. Among 185 survivors, 199 SNs occurred, 53% in the CNS. Survivors reported more multiple chronic medical conditions (CMCs; odds ratio...


Source: Cancer Weekly (2008-07-29)

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