Cancer Weekly
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Apoptosis
Reports from University of California highlight recent research in apoptosis
July 29th, 2008
"Freshly isolated untreated NK cells undergo rapid apoptosis and lose their cytotoxic function upon the addition of F(ab')(2) fragment of anti-CD16 antibodies. Loss of NK cell cytotoxic function after treatment with F(ab')(2) fragment of anti-CD16 antibody can be seen against K562 and UCLA-2 oral tumor cells when either added immediately in the co-cultures of NK cells with the tumor cells or after pre-treatment of NK cells with the antibody before their addition to the tumor cells," researchers in the United States report. "Addition of Interleukin-2 (IL-2) in combination with anti-CD16 antibody to NK cells delayed the induction of DNA fragmentation in NK cells, and even...
Source: Cancer Weekly (2008-07-29)
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