Breast Cancer

Recent studies from University of Turin add new data to breast cancer

Published in Cancer Weekly, July 29th, 2008

According to recent research published in the Journal of Translational Medicine, "Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antibody-dependent cellular cytotoxicity (ADCC) by triggering Fc gamma RIII on natural killer (NK) cells."

"This study addresses the correlation between overall NK function and trastuzumab's clinical activity. Clinical and immunological responses were assessed in 26 patients receiving trastuzumab monotherapy as maintenance management after chemotherapy (8 mg/kg load and then...

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Source: Cancer Weekly (2008-07-29)

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