Published in Cancer Weekly, August 5th, 2008
"Cynomolgus monkeys were treated once with 5, 15, or 30 mg/kg MLN8866 via a 20 min intravenous infusion. MLN8866 exposure (Cmax and AUC0-4 day) was determined by quantifying MLN8866 levels in serum. The increase in MLN8866 exposure was approximately dose proportional," wrote F.Y. Hsieh and colleagues, Nextcea,...
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