Cancer Weekly
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Angiogenesis
Findings from S. Kesari and co-researchers advance knowledge in angiogenesis
August 5th, 2008
"We conducted a phase II study of the combination of temozolomide and angiogenesis inhibitors for treating adult patients with newly diagnosed glioblastoma. Patients who had stable disease following standard radiation therapy received temozolomide for 5 days in 28-day cycles, in combination with daily thalidomide and celecoxib," scientists writing in the journal Neuro - Oncology report. "Patients were treated until tumor progression or development of unacceptable toxicity. Four-month progression-free survival (PFS) from study enrollment was the primary end point, and overall survival (OS) was the secondary end point. In addition, we sought to correlate response...
Source: Cancer Weekly (2008-08-05)
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