Cancer Weekly
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Angiogenesis
Research from Stanford University provides new data about angiogenesis
August 5th, 2008
According to recent research from the United States, "Angiogenesis, formation of new vasculature, is critical to cancer growth. Agents that block angiogenesis, in particular bevacizumab, a monoclonal antibody that binds vascular endothelial growth factor, the key ligand in angiogenesis, have become all important option for many patients with non-small cell lung cancer (NSCLC)." "Activity was first demonstrated in Eastern Cooperative Oncology Group E4599, a large phase 3 trial that randomized patients with newly diagnosed, nonsquamous NSCLC to receive carboplatin/paclitaxel with or without bevacizumab at 15 mg/kg every 3 weeks. The study demonstrated significant...
Source: Cancer Weekly (2008-08-05)
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