Cancer Weekly
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Angiogenesis
Studies from D. Herr et al provide new data on angiogenesis
August 5th, 2008
"This study examined the potential role of Angiotensin 11 for the regulation of angiogenesis associated genes in receptor positive and negative human breast cancer. Expression of different Renin-Angiotensin system (R-AS) components in human breast cancer tissue was investigated using immunofluorescence, and in a receptor positive (MCF-7) and receptor negative (NIDA-MB 468) breast cancer cell line by perfortning immunocytochemistry and RT-PCR," investigators in Ulm, Germany report. "Both cell lines were stimulated with Angiotensin 11 and Angiotensin 11 receptor type I (At, R) blocker Candesartan, and geneexpression of vascular endothelial growth factor(VEGF),...
Source: Cancer Weekly (2008-08-05)
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