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Bladder Cancer
Findings in bladder cancer reported from B.A. Hadaschik and co-researchers
August 5th, 2008
According to a study from Vancouver, Canada, "Bladder cancer is the second most common genitourinary malignancy. At initial diagnosis, similar to 70% of cases are nonmuscle-invasive; however, current treatment options for superficial disease are of limited efficacy because many patients will develop recurrent tumors." "The purpose of this study was to examine two replication-competent oncolytic vesicular stomatitis virus (VSV) strains as intravesical agents in an orthotopic murine model of high-grade bladder cancer. Four human bladder cancer cell lines (RT4, MGH-U3, UM-UC3, and KU-7) were treated with either wild-type VSV or a mutant Delta 51M variant (AV3) in vitro....
Source: Cancer Weekly (2008-08-05)
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