Cancer Weekly
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Bladder Cancer
Radboud University publishes research in bladder cancer
August 5th, 2008
According to a study from Netherlands, "To analyse and compare the concentration of plasminogen activator (PA), urokinase-type PA (uPA), tissue-type PA (tPA), PA inhibitor (PAI)-1 and PAI-2, and the complexes uPA-PAI-1 and tPA-PAI-1 and calculated uPA and tPA uncomplexed with PAI-1 ('free') in urothelial cell carcinoma and matched benign urothelium, and in renal cell carcinoma (RCC) and matched benign renal tissue. Tissue samples were obtained during cystectomy (33 patients) and nephrectomy (55), and specific enzyme-linked immunosorbent assays were used to assess the PA components in extracts of these tissues." "Tissue levels of uPA-PAI-1 and tPA-PAI-1, but also PAI-1...
Source: Cancer Weekly (2008-08-05)
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