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Cancer Gene Therapy
New findings from University of Texas, Institute of Molecular Medicine in the area of cancer gene therapy described
August 12th, 2008
A new study, '1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells,' is now available. "Prostate specific membrane antigen (PSMA) expression correlates with prostate cancer grade and is increased in hormone-refractory prostate cancer. The increased expression of PSMA following androgen deprivation therapy may be a consequence of the down-regulation of PSMA expression by androgen," scientists in the United States report. "Moreover, 1alpha,25-dihydroxyvitamin D3 (1,25-VD) has been shown to suppress prostate cancer progression as well as cell motility and invasion. Since PSMA is positively correlated with...
Source: Cancer Weekly (2008-08-12)
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