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Cancer Gene Therapy

University of Granada publishes research in cancer gene therapy

Published in Cancer Weekly, August 12th, 2008

Research findings, 'Combined therapy using suicide gef gene and paclitaxel enhances growth inhibition of multicellular tumour spheroids of A-549 human lung cancer cells,' are discussed in a new report. According to a study from Granada, Spain, "The low efficiency of conventional therapies in achieving long-term survival of lung cancer patients calls for development of novel options. The potential use of combined gene therapy is under intensive study."

"One approach uses the expression of genes encoding cytotoxic proteins that affect cellular viability. The gef gene from E. coli, identified as a member of a gene family encoding homologous cell-killing functions,...

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