Cancer Weekly
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Angiotensins
New angiotensins data have been reported by O. Arrieta and co-authors
August 12th, 2008
"Astrocytomas develop intense vascular proliferation, essential for tumour growth and invasiveness. Angiotensin II ( ANGII) was initially described as a vasoconstrictor; recent studies have shown its participation in cellular proliferation, vascularisation, and apoptosis," scientists in Mexico report. "We conducted a prospective study to evaluate the expression of ANGII receptors - AT1 and AT2 - and their relationship with prognosis. We studied 133 tumours from patients with diagnosis of astrocytoma who underwent surgery from 1997 to 2002. AT1 and AT2 were expressed in 52 and 44% of the tumours, respectively, when determined by both reverse transcriptase - polymerase...
Source: Cancer Weekly (2008-08-12)
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