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Astrocytoma Immunology

New astrocytoma immunology research from University Hospital outlined

Published in Cancer Weekly, August 12th, 2008

Fresh data on astrocytoma are presented in the report 'WT1 expression distinguishes astrocytic tumor cells from normal and reactive astrocytes.' "Particularly in small brain biopsies, it might be difficult to distinguish reactive astrogliosis from low-grade or infiltration zones of high-grade astrocytomas. So far no immunohistochemical marker allows a reliable distinction," scientists writing in the journal Brain Pathology report.

"Recently, the over-expression of Wilms' tumor gene product WT1 was reported in astrocytic tumor cells. However, no sufficient data on WT1 expression in normal or reactive astrocytes are available. Therefore, we investigated WT1...

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