Life Sciences

Reports from University of Michigan, Comprehensive Cancer Center highlight recent research in life sciences

Published in Cancer Weekly, August 12th, 2008

Researchers detail in 'GVHD pathophysiology: is acute different from chronic,' new data in life sciences. According to a study from the United States, "Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation (HCT). GVHD occurs in acute and chronic forms."

"Acute GVHD usually manifests within 100 days following HSCT. It is induced by donor T cells responding to the mismatched host polymorphic histocompatibility antigens. Chronic GVHD generally manifests later (>100 days) and has some features of autoimmune diseases. It may develop either de novo or following resolution of -or as an extension of -acute GVHD. Chronic...

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Source: Cancer Weekly (2008-08-12)

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