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Medulloblastoma Cell Biology

Study findings from Dalian Medical University broaden understanding of medulloblastoma cell biology

Published in Cancer Weekly, August 12th, 2008

Investigators publish new data in the report 'Correlative analyses of notch signaling with resveratrol-induced differentiation and apoptosis of human medulloblastoma cells.' "Altered Notch signaling seems linked with medulloblastoma (MB) formation and resveratrol exhibits anti-medulloblastoma effects. However, the influence of resveratrol in Notch signaling of MB cells has not been described," researchers in People's Republic of China report.

"This issue was addressed here by checking Notch1 and Notch2 statuses in three MB cell lines with and without resveratrol treatment. Notch1 and Notch2 were detected in the cytoplasm of three cell lines under normal condition, which...

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