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Cancer Gene Therapy
Researchers from Kinki University, Department of Urology detail findings in cancer gene therapy
August 19th, 2008
A new study, 'Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation,' is now available. According to a study from Osaka, Japan, "The tumor suppressor gene MMAC/PTEN located on chromosome10q23.3 has dual phosphatase activity in the phosphoinositide-3-kinase signaling pathway and inhibits Akt activation, a serine-threonine kinase, which is involved in proliferative and antiapoptotic pathways. Furthermore, MMAC/PTEN is frequently inactivated in a variety of tumors including prostate cancer." "In this study, we generated a new type of gene transfer drug, GelaTen, which is a microsphere of cationized gelatin hydrogels incorporating...
Source: Cancer Weekly (2008-08-19)
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