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Cancer Gene Therapy
Researchers from University of Texas, M. D. Anderson Cancer Center discuss findings in cancer gene therapy
August 19th, 2008
New investigation results, 'Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma,' are detailed in a study published in Molecular Cancer Therapeutics. "Src family tyrosine kinases (SFK) play an important role in growth and metastasis of many types of human malignancies. However, their significance in Ewing's sarcoma remains to be elucidated," investigators in the United States report. "The purpose of this study was to evaluate the role of Lyn, one member of the SFK, in Ewing's sarcoma growth and metastasis and to determine whether a SFK inhibitor can induce Ewing's tumor regression. Lyn was expressed and activated in TC71, A4573, and SK-ES human...
Source: Cancer Weekly (2008-08-19)
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