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Gene Therapy
Study results from Tianjin Medical University, Life Science Research Center in the area of gene therapy published
August 19th, 2008
New research, 'Targeting alpha-fetoprotein represses the proliferation of hepatoma cells via regulation of the cell cycle,' is the subject of a report. According to recent research published in the journal Clinica Chimica Acta, "AFP is a biomarker for primary liver cancer, yet little is known about its effect in the pathogenesis of hepatoma. We examined how AFP modulates the proliferation of hepatoma cells." "Recombinant adenovirus expressing siRNA against AFP was created. The repression of cell proliferation in vitro and growth of hepatoma in vivo were examined by colony formation assay and tumor xenograft in SCID mice, respectively. Cell cycle was assayed by...
Source: Cancer Weekly (2008-08-19)
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