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Immunization
Researchers from Seoul National University, Department of Nuclear Medicine describe findings in immunization
August 19th, 2008
Current study results from the report, 'Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy,' have been published. "We examined the merits of combinatorial hMUC1 vaccination and hNIS radioiodine gene therapy and evaluated its tumoricidal effects in an animal tumor model. CMNF (CT26 expressing hMUC1, hNIS, and firefly luciferase) cells were transplanted into 28 mice, and 4 and 11 days after tumor challenge, tumor-bearing mice were immunized i.m. with pcDNA3.1 or pcDNA-hMUC1 vaccine and subsequently administered PBS or (131)I i.p," scientists writing in the journal Molecular Cancer Therapeutics report. "[four groups (7...
Source: Cancer Weekly (2008-08-19)
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