Cancer Weekly
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Acute Myelocytic Leukemia
Study results from N.C. Gorin and colleagues broaden understanding of acute myelocytic leukemia
August 19th, 2008
According to recent research from Paris, France, " Patients with acute myelocytic leukemia carrying inversion 16 (inv16) or t(8;21) have a better initial response to high-dose cytarabine than patients without these chromosomal abnormalities. They presently do not undergo transplantation in first remission (CR1), but there is concern about late relapses." "Patients and Methods From 1990 to 2004, 325 adult patients received transplantations in CR1 (159 patients with inv16 and 166 patients with t(8;21), including 35 and 60 patients, respectively, with additional chromosomal abnormalities). Genoidentical allografts were performed in 64 patients with inv16 and 81 patients...
Source: Cancer Weekly (2008-08-19)
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