Cancer Weekly
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Acute Promyelocytic Leukemia
Studies conducted at S.J. Collins et al on acute promyelocytic leukemia recently published
August 19th, 2008
"Purpose of review All-trans retinoic acid therapy of acute promyelocytic leukemia represents the most successful example of differentiation-induction therapy in clinical oncology. However, acute promyelocytic leukemia represents only a small minority (10-15%) of the myeloid leukemias," scientists in the United States report. "Recent studies provide significant insight into why some myeloid leukemias respond dramatically to all-trans retinoic acid mediated differentiation therapy, whereas others do not. Recent findings Utilizing in-vitro experimental models of all-trans retinoic acid triggered myeloid leukemia differentiation, specific genes that are important...
Source: Cancer Weekly (2008-08-19)
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