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Cancer Weekly

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Cancer Gene Therapy



New cancer gene therapy research reported from Medical College



August 19th, 2008

According to recent research published in the journal Advances in Therapy, "The purpose of this study was to determine whether ultrasound exposure combined with microbubble destruction could be used to enhance non-viral gene delivery in human pancreatic carcinoma cells (PANC-1). The study was performed with four experimental groups: Group P, plasmid alone; Group P+M, plasmid and microbubbles; Group P+U, plasmid and ultrasound; Group P+U+M, plasmid with ultrasound and microbubbles."

"Plasmid DNA encoding enhanced green fluorescent protein (pEGFP) was gently mixed with commercially available ultrasound microbubble contrast agents (SonoVue (R); Bracco Diagnostics...


Source: Cancer Weekly (2008-08-19)

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