Cancer Weekly
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Cancer Gene Therapy
New findings from K. Kelly and co-researchers in the area of cancer gene therapy described
August 26th, 2008
According to recent research from the United States, "Many cancers can cause disability and pain by invading nerves. In particular, prostate carcinoma has a high propensity for neural invasion (NI) at an early stage." "Attempted surgical treatment of tumors with NI often leads to erectile dysfunction and deteriorated quality of life. Therefore, there is a need for novel modalities that will selectively target cancer cells while preserving neural function. Herpes simplex viruses (HSVs) have a natural trophism for peripheral nerves. We hypothesized that oncolytic therapy using HSV engineered to minimize neurotoxicity would be appropriate for this clinical setting....
Source: Cancer Weekly (2008-08-26)
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