Cancer Weekly
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Cancer Gene Therapy
Reports outline cancer gene therapy research from University of Granada
August 26th, 2008
According to recent research from Granada, Spain, " Gene therapy is a new method used to induce cancer cell differentiation. Our group previously showed that transfection of the gef gene from Escherichia coli, related to cell-killing functions, may be a novel candidate for cancer gene therapy." "Its expression leads to cell cycle arrest unrelated to the triggering of apoptosis in MS-36 melanoma cells. Objectives To determine the basis of the antiproliferative effect of the gef gene in this cell line. Transmission electron microscopy, apoptosis analysis by confocal microscopy, flow cytometry and immunocytochemical analysis were used. Ultrastructural analysis showed a...
Source: Cancer Weekly (2008-08-26)
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