Cancer Weekly
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Cancer Vaccines
New cancer vaccines study results from Mayo Clinic, Medical Department described
August 26th, 2008
"The Edmonston vaccine strain of measles virus has potent and selective activity against a wide range of tumors. Tumor cells infected by this virus or genetically modified strains express viral proteins that allow them to fuse with neighboring cells to form syncytia that ultimately die," researchers in the United States report. "Moreover, infected cells may produce new virus particles that proceed to infect additional tumor cells. We present a model of tumor and virus interactions based on established biology and with proper accounting of the free virus population. The range of model parameters is estimated by fitting to available experimental data. The stability of...
Source: Cancer Weekly (2008-08-26)
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